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Elísio Costa Selected Research

Crigler-Najjar Syndrome

12/2015Performance of In Silico Tools for the Evaluation of UGT1A1 Missense Variants.
5/2009Identification of a novel deletion in UDP-glucuronosyltransferase gene in a patient with Crigler-Najjar syndrome type I.
1/2006Hematologically important mutations: bilirubin UDP-glucuronosyltransferase gene mutations in Gilbert and Crigler-Najjar syndromes.
1/2006Analysis of the UDP-glucuronosyltransferase gene in Portuguese patients with a clinical diagnosis of Gilbert and Crigler-Najjar syndromes.

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Elísio Costa Research Topics

Disease

17Inflammation (Inflammations)
11/2017 - 01/2008
13Chronic Kidney Failure (Chronic Renal Failure)
06/2021 - 01/2010
11Chronic Renal Insufficiency
06/2016 - 01/2008
6Anemia
06/2016 - 01/2010
4Fibrosis (Cirrhosis)
05/2017 - 01/2015
4Crigler-Najjar Syndrome
12/2015 - 01/2006
3Frailty
11/2021 - 10/2020
3Body Weight (Weight, Body)
06/2016 - 04/2016
3Hypoxia (Hypoxemia)
04/2016 - 01/2015
3Insulin Resistance
01/2016 - 01/2012
3Gilbert Disease
03/2012 - 04/2002
3Hereditary Spherocytosis
02/2011 - 03/2010
2Chronic Disease (Chronic Diseases)
10/2020 - 09/2018
2Hemolysis
11/2018 - 12/2014
2Overweight
11/2017 - 01/2013
2Hypertension (High Blood Pressure)
04/2016 - 03/2016
2Obesity
01/2016 - 08/2014
2Hyperbilirubinemia
12/2015 - 01/2006
2Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2015 - 08/2014
2Arteriovenous Fistula
05/2014 - 10/2013
2Lymphopenia (Lymphocytopenia)
07/2008 - 05/2008
1COVID-19
01/2021
1Venous Thrombosis (Deep-Vein Thrombosis)
10/2018
1Thrombosis (Thrombus)
10/2018
1Drug-Related Side Effects and Adverse Reactions
09/2018
1Weight Gain
11/2016
1Iron Overload
05/2016
1Pediatric Obesity
08/2014
1Dyslipidemias (Dyslipidemia)
01/2013
1Iron Deficiencies
01/2013
1Cardiovascular Diseases (Cardiovascular Disease)
01/2012
1Hemolytic Anemia
06/2010
1Protein Deficiency
06/2010
1Renal Insufficiency (Renal Failure)
01/2010
1Hypertrophy
01/2010
1Polycythemia (Erythrocytosis)
01/2010
1Tachycardia (Tachyarrhythmias)
01/2010
1Infections
11/2007

Drug/Important Bio-Agent (IBA)

12ErythropoietinFDA Link
06/2016 - 01/2008
9IronIBA
11/2017 - 01/2008
5BilirubinIBA
01/2015 - 03/2010
4Pharmaceutical PreparationsIBA
01/2021 - 12/2015
4HepcidinsIBA
11/2017 - 01/2008
4Proteins (Proteins, Gene)FDA Link
12/2015 - 01/2008
4AdiponectinIBA
08/2014 - 10/2012
3LipidsIBA
01/2016 - 10/2012
3C-Reactive ProteinIBA
01/2016 - 01/2015
3Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
12/2015 - 01/2006
3Interleukin-6 (Interleukin 6)IBA
04/2015 - 05/2008
2Biomarkers (Surrogate Marker)IBA
11/2021 - 11/2016
2Uridine Diphosphate (UDP)IBA
12/2015 - 04/2002
2oxidized low density lipoproteinIBA
01/2015 - 10/2012
2Transferrin (beta 2 Transferrin)IBA
01/2015 - 01/2013
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2013 - 01/2012
2Membrane Proteins (Integral Membrane Proteins)IBA
06/2010 - 01/2008
2bilirubin glucuronoside glucuronosyltransferaseIBA
01/2006 - 11/2005
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2018
12,2'-azobis(2-amidinopropane) (ABAP)IBA
11/2018
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
10/2018
1Biological ProductsIBA
11/2016
1salicylhydroxamic acid (SHAM)IBA
06/2016
1Pancreatic Elastase (Elastase)IBA
04/2016
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
04/2016
1Saline SolutionIBA
04/2016
1AdipokinesIBA
01/2016
1AntibodiesIBA
12/2015
1InterleukinsIBA
01/2015
1Biocompatible Materials (Biomaterials)IBA
12/2014
1Iron-Regulatory Proteins (Iron-Responsive Element Binding Proteins)IBA
12/2014
1Irritants (Vesicants)IBA
12/2014
1zirconium oxide (zirconia)IBA
04/2014
1S 27IBA
10/2013
1Cell-Free Nucleic AcidsIBA
10/2013
1Apoprotein(a) (Apolipoprotein (a))IBA
10/2012
1Lipoprotein(a)IBA
10/2012
1Insulin (Novolin)FDA Link
01/2012
1Apolipoproteins AIBA
01/2012
1ApolipoproteinsIBA
01/2012
1Triglycerides (Triacylglycerol)IBA
01/2012
1Apolipoproteins B (ApoB)IBA
01/2012
1Hemoglobins (Hemoglobin)IBA
02/2011
1AnkyrinsIBA
06/2010
1SpectrinIBA
06/2010
1CatecholaminesIBA
01/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2010
1HematinicsIBA
01/2010
1Interleukin-7 (Interleukin 7)IBA
07/2008
1CytokinesIBA
05/2008
1QuinolonesIBA
11/2007
1ticarcillin-clavulanic acid (Timentin)FDA Link
11/2007
1N 30IBA
07/2007

Therapy/Procedure

16Therapeutics
05/2017 - 01/2008
13Renal Dialysis (Hemodialysis)
06/2021 - 01/2008
4Hemodiafiltration
09/2016 - 05/2014
4Nephrectomy
06/2016 - 01/2015
3Polypharmacy
01/2021 - 09/2018
2Blood Vessel Prosthesis
05/2017 - 11/2016
1Activities of Daily Living (ADL)
09/2018
1Central Venous Catheters
05/2014
1Catheters
10/2013